The main causes of infertility in humans are represented by a low volume of semen. In addition, other causes may cause this issue to the limited mobility of sperm or poor sperm quality. A low volume of semen can have a negative effect on the quality of sexual life and self-confidence. Many men suffer from this condition which is caused by many factors. The male infertility is associated with alterations in sperm parameters. Sperm abnormalities may be due to infectious causes, environmental, trauma, and malformations and genetic. Different genetic causes of male infertility have been described such as CFTR gene mutations, syndrome, chromosomal translocations and micro deletions of chromosome Y.
Among infertile men, the frequency of chromosomal abnormalities is increased. The men carrying a translocation produce a significant percentage of sperm with a combination of the unbalanced translocation, leading to a risk more or less important imbalance for their offspring.
Currently, the mechanisms that determine the genetic quality of gametes are poorly understood. Some genetic factors such as apoptosis may be involved in the meiotic process in germ cells.
After semen collection by self-masturbation in a sterile container and liquefaction at room temperature, sperm parameters were analyzed: volume and pH of the ejaculate, concentration, mobility rapid progressive, slow and non-progressive and vitality of sperm.
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